Translational Research Committee Expertise
The people listed below form the TReC Committee, and will provide informal advice and guidance to assist with working up a submission, ready to present to a panel.
Dr. Matt Smalley (Scientific Chair)
Area of expertise: Breast Cancer Biology
Specifically: Mouse models of breast cancer; cancer stem cells; flow sorting.
Prof. John Chester (Clinical Chair)
Area of expertise: Bladder cancer, germ cell tumours and head/neck cancers.
Specifically: Trials for bladder and head/neck cancers, and in stratified medicine
Prof. Malcolm Mason
Area of expertise: Urological cancer
Specifically: Phase III Trials, Translational research.
Prof. Oliver Ottmann
Area of expertise: Haematology
Specifically: Early phase clinical trials, small molecule therapeutics, biologicals, clinical translational science, drug development.
Prof. Peter Barrett-Lee
Area of expertise: Breast Cancer Biology / Breast Cancer Treatments
Specifically: Consultant and Professor of Breast Cancer Studies
Prof. Chris Pepper
Area of expertise: Lymphoid haematological malignancies (e.g. CLL Myeloma)
Specifically: Drug Development, rational drug combination design/validation, drug resistance mechanisms.
Prof. Angela Casini
Area of expertise: Medicinal and Bioinorganic Chemistry
Specifically: Synthetic chemistry, design of enzyme inhibitors, development of ex vivo methods for drug screening, target identification studies on anticancer compounds, toxicity screenings.
Dr. Andrew Westwell
Area of expertise: Medicinal Chemistry / Pre Clinical Drug Discovery
Specifically: Synthetic medicinal chemistry
Dr. Rob Jones
Area of expertise: Phase 1 trials
Specifically: Early Phase protocol development, DNA checkpoint inhibitors.
Dr. Steve Knapper
Area of expertise: Myeloid haematological malignancies, Molecularly targeted therapies, TKIs
Specifically: Interface between pre-clinical characterisation of new agents and early phase studies. "Back to bench" testing.
Dr. John Staffurth
Area of expertise: Radiotherapy, prostate cancer, bladder cancer, immunology
Specifically: All aspects of technical radiotherapy, molecular radiotherapy, functional imaging, translational immunology, late phase trial design.
Dr. Julia Gee
Area of expertise :Endocrine resistance in breast cancer, clinical trial sample profiling during drug treatment.
Specifically: Immunohistochemistry; development and use of in vitro models; gene microarray studies.
Dr Andy Godkin
Area of expertise: Immunology, hepatology, gastroenterology.
Specifically: Laboratory research and translational medicine.
Area of expertise: Early phase research delivery.
Specifically: Research nursing, chemotherapy nursing.
Dr Laura Newell
Area of expertise: Technology Transfer
Specifically: Intellectual property; translational funding; research commercialisation.